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Mupirocin Ointment for Acute Radiation Oral Mucositis Prevention
Posted: 10/20/2025 | By: Chase Doyle

Introduction: This phase III study, published in JAMA Oncology, investigates whether bacterial decolonization with mupirocin may be effective in alleviating severe acute radiation oral mucositis (grade ≥ 3) in patients undergoing radiotherapy for nasopharyngeal carcinoma.

Question 1 of 5

What was the primary objective of the study?

Choose 1

A
To compare the cost-effectiveness of mupirocin vs other antibiotics for alleviating oral mucositis in patients undergoing radiotherapy for nasopharyngeal carcinoma
B
To assess the long-term survival rates in nasopharyngeal carcinoma patients undergoing radiotherapy
C
To evaluate the efficacy of bacterial decolonization with mupirocin nasal ointment in reducing severe acute radiation oral mucositis (grade ≥ 3) compared with standard of care treatment
D
To investigate the impact of radiotherapy duration on Staphylococcus aureus colonization

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