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Radiopharmaceuticals for Treatment of Metastatic Castration-Resistant Prostate Cancer
Posted: 10/21/2022 | By: Larry Rosenberg, PhD

Question 2 of 5

Treatment of men with mCRPC using LuPSMA can result in off-target effects such as nephrotoxicity because:

Choose 1

A
PSMA is also expressed in the kidneys
B
The drug localizes primarily in the kidneys
C
Renal tubules are highly sensitive to radiation
D
PSMA in the prostate becomes oversaturated with LuPSMA, leading to binding in the kidneys

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